Cerca Articoli

Scientists Discover First of a New Class of Extrasolar Planets

Whitney Clavin-  (626) 354-4673/354-5011Jet Propulsion Laboratory, Pasadena, Calif. Donald Savage-  (202) 358-1547NASA Headquarters, Washington, D.C.

Frontiers Records is pleased to announce the signing of STAN BUSH

Roche Pharmaceuticals: PEGASYS(r) and COPEGUS(r) Dominate Hepatitis C Treatment Abstracts

European Association for the Study of the Liver (EASL) Conference To Feature 17 Abstracts on New Generation Pegylated Interferon

WHO Executive Body reaffirms WHO leadership on key issues for Global Public Health

QUALCOMM Showcases 3G Technologies and Applications at 3GSM World Congress in Cannes, France

Company Continues to Drive the Wireless Market to 3G with its Innovative Products and Solutions.

THE FANCONI ANAEMIA/BRCA PATHWAY

Fanconi anaemia (FA) is a rare genetic cancer-susceptibility syndrome that is characterized by congenital abnormalities, bone-marrow failure and cellular sensitivity to DNA crosslinking agents. Seven FA-associated genes have recently been cloned, and their products were found to interact with well-known DNA-damage-response proteins, including BRCA1, ATM and NBS1. The FA proteins could therefore be involved in the cell-cycle checkpoint and DNA-repair pathways. Recent studies implicate the FA proteins in the process of repairing chromosome defects that occur during homologous recombination, and disruption of the FA genes results in chromosome instability ”€ a common feature of many human cancers.